B Pharm 6 Sem Biopharmaceutics And Pharmacokinetics Imp Questions 2024

In this post B pharm 6th sem biopharmaceutics and Pharmacokinetics imp questions are given for 2024. 

In this set, an attempt has been made to include all those questions which have been asked in the previous examination. 

Along with this, those possible questions have been included in the Biopharmaceutics and Pharmacokinetics 6th semester question paper given below, which fall in the category of very important from the exam point of view and they can be asked again. 

Therefore do not skip any question given here. 

Write down the important questions of biopharmaceutics and Pharmacokinetics given here in sequence in your notebook. 

After that, to clear your concept on this topic read the related lesson in the textbook recommended by the university two to three times and try to understand the meaning of the lesson. 

If you have any difficulty in understanding the meaning, consult your professor. 

Once your concept is clear on this topic, you can write the answer to any question in your own words. 

Apart from these questions, you will be able to understand and write answers to many questions. 

By writing the answers to these b pharm 6 sem biopharmaceutics and Pharmacokinetics imp questions in your own words, you will be able to assimilate them easily and they will remain in your mind for a long time. 

Your time will also be saved in revising those answers. 

Many questions can be asked from the biopharmaceutics and Pharmacokinetics question bank given here in the exam question paper. 

It is not that questions should be asked only in the format given here, they can also be presented in a twisted manner. 

Therefore your preparation should be solid. 

After receiving the question paper on this subject in the examination hall, first of all, ensure that it is error-free and no page is missing. 

In case of any error, inform the invigilator and request for another error-free question paper. 

Start writing answers only after reading the instructions on the first page of the question paper. 

Write an informative answer within the recommended number of words. 

Write long answers to biopharmaceutics and pharmacokinetics 6th semester important questions using 500 words and short answers using 200 words. 

The format of the set given here has been set as per previous year question papers of biopharmaceutics and pharmacokinetics, so that students can understand the pattern of questions asked in the exam and can prepare accordingly. 

Let's solve them.

Biopharmaceutics And Pharmacokinetics Questions

Biopharmaceutics And Pharmacokinetics 6th Semester Pharma Important Questions

  • Describe the kinetics of the dose-dependent model with the help of an equation.
  • Write in detail about dosage form characteristics and pharmaceutical ingredients influencing the GI absorption of a drug.
  • Discuss the binding of the drug to the blood component.
  • Elaborate in detail about the approaches to improve the bioavailability of BCS class II drugs.
  • Explain the role of physiological barriers to drug distribution.
  • Draw a plasma drug concentration Vs time profile of a single oral administration stating all pharmacokinetic parameters.
  • Elaborate in detail about the renal excretion of the drug.
  • Write short notes on the following:- (a) Mamillary model (b) Outline the sources of non-linearity in connection to ADME (c) Factors affecting renal clearance.
  • Write the note on tubular reabsorption.
  • Discuss the Bioequivalence study protocol.
  • Write short notes on the following:- (a) Pre-systemic metabolism (b) Types of pharmacokinetic models (c) Perfusion rate (d) Clinical pharmacokinetics (e) Competitive binding with example.
  • Explain the drug absorption by any two non-par oral extravascular routes.
  • Outline the steady state level of the drug on repeated dose administration.
  • Write a short answer on the following:- (a) Endocytosis (b) Bioequivalence (c) Cmax and Tmax (d) Capacity limited kinetics (e) Equate the rate of excretion (f) Recall Phase I and II reactions. 
  • Explain the binding of the drug to human serum albumin.
  • Write the name of the non-renal route of excretion.
  • Write short notes on the following:- (a) Non-compartmental analysis (b) Importance of the pharmacokinetic model.
  • Describe the objective and approaches of invitro-invivo correlation.
  • Explain the elimination rate constant.
  • Write a short answer on the following:- (a) Bioavailability (b) Loading and Maintenance dose (c) GFR (d) Active and Passive transport (e) Total clearance.
  • Explain the term BCS classification.
  • Write the short notes on the following:- (a) Catenary model (b) Open compartment vs. closed compartment apparatus (c) Absolute and relative bioavailability (d) Significance of protein binding.
  • Explain the patient-related factors influencing the absorption of drugs through GIT with examples.
  • Write the name and the type of dosage form used to test in Type I and Type II dissolution apparatus.
  • Write a detailed description of the Measurement of bioavailability.
  • Estimate the Pharmacokinetics parameters of the drug using the Sigma minus method adopting a compartment open model for a bolus Intravenous Injection.
  • Discuss in detail about invitro dissolution models.
  • Explain the Michaelis-mention equation and Michaelis-mention method of estimating parameters.
  • Discuss the two-compartment model.
  • Write short notes on the following:- (a) Method of residuals (b) MRT (c) Non-linear pharmacokinetics (d) Drug disposition (e) Therapeutic window (f) Biological half-life (t½).
  • Define prodrug with one example.
  • Explain the physiological models.
  • Write the short answer on the following:- (a) Drug interaction (b) Name the principal process in the urinary excretion of drugs. 
  • Detail the principle mechanism of transportation of drug molecules across various membranes.
  • Write the short notes on the following:- (a) Tissue Permeability (b) Steady-state concentration (c) AUC (d) Testing of kidney function (e) Multi-dose. 
  • Write short notes on the following:- (a) Tissue binding of the drug (b) Theories of drug dissolution (c) First pass metabolism (d) Apparent volume of distribution.

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